Collodion baby, lamellar ichthyosis; A report of two cases and literature review
Keywords:
Ichthyosis, Collodion baby, Social StigmatizationAbstract
Abstract: Ichthyosis are disorders of cornification characterized clinically by a pattern of scaling and histologically by hyperkeratosis. Babies with these conditions present as collodion babies that are covered in thick, taut, cellophane like membranes with associated bilateral ectropion and eclabium. The membrane sheds over a few days to weeks after birth to reveal the true nature of the underlying condition which may either be a lamellar ichthyosis, a recessive x-linked ichthyosis, congenital ichthyosiform erythroderma, harlequin ichthyosis or a normal skin variant otherwise known as the Self-healing Collodion baby. We present two cases of collodion babies that were seen in our hospital within a space of two months.
The first case was considerably successfully managed in the neonatal period but social stigmatization prevented follow up while the second case was discharged against medical advice by the parents after 48 hours of admission.
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