Statut en vitamine D du couple mère-enfant a Libreville au Gabon en 2024
Keywords:
status, vitamin D, mother, newborn, Libreville- GabonAbstract
Introduction: Vitamin D is essential for the proper regulation of many bodily systems, as well as for the normal growth and development of human beings.
Objective: To assess the vitamin D status of mother-child pairs in Libreville in 2024.
Patients and methods: This was a multicenter, prospective, crosssectional study conducted from August 1st to February 20th, 2025. Vitamin D levels were measured in mother-child pairs in the delivery room. A vitamin D level <30 ng/mL defined hypovitaminosis D.
Results: Two hundred and eighty mother-newborn pairs were included in the study. The mean age of the mothers was 28.1±6.8 years (range 15 to 45 years). The average number of prenatal contacts was 5.0±2.0. Vitamin D deficiency was observed in 57.9% of mothers, with 20.8% exhibiting a severe deficiency. In newborns, the mean gestational age was 38.6 ± 1.7 weeks (range 32 to 42 weeks) with a male-to-female ratio of 1.2. The mean birth weight was 3096.3 ± 516.4 g (range 1700 to 4250 g). Vitamin D deficiency was found in 78.2% of newborns. In this group, 44.3% had a severe vitamin D deficiency. Vitamin D deficiency in the newborn was significantly associated with intrauterine growth restriction (p=0.005). There was a strong correlation between maternal and neonatal vitamin D levels (r=0.784).
Conclusion: Vitamin D deficiency is a real problem in the motherchild dyad in Libreville. Maternal vitamin D supplementation during pregnancy should be systematic. Similarly, supplementation of the newborn is beneficial and should be continued beyond 6 months.
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