Sacrococcygeal teratoma in a newborn : A case report
Keywords:
Sacrococcygeal Teratoma, Resource limited settings, Early intervention.Abstract
Background: Sacrococcygeal teratoma is an extragonadal teratoma arising from multipotent stem cells from the Hansen node located around the coccyx. In our setting, the neonatal and pediatric surgery units each have two documented cases of sacrococcygeal teratoma per year. This gives an estimated annual incidence of 1 case per 100,000 live births in Dares Salaam. Given the rarity of the condition and because early diagnosis and surgical intervention improve the overall outcome
Case Presentation: We present a 2-day-old female baby who was referred to our facility with a gluteal mass. After the initial workup, surgical resection and biopsy confirmed a teratoma. The surgery was done successfully and the child fully recovered with an excellent outcome.
Conclusion: Early recognition, referral to the appropriate center, and intervention averts morbidity and mortality and improves the quality of life in neonates with sacrococcygeal teratoma. Serial Alfa Fetoprotein measurements are a good indicator to monitor progress
References
Schropp KP, Lobe TE, Rao B, Mutabagani K, Kay GA, Gilchrist BF, et al. Sacrococcygeal teratoma: the experience of four decades. J pediatric surgery. 1992;27(8):1075–9.
Rescorla FJ, Sawin RS, Coran AG, Dillon PW, Azizkhan RG. Long-term outcome for infants and children with sacrococcygeal teratoma: a report from the Children's Cancer Group. J pediatric surgery. 1998;33(2):171–6.
Lahdenne P, Heikinheimo M, Nikkanen V, Klemi P, Siimes MA, Rapola J. Neonatal benign sacrococcygeal teratoma may recur in adulthood and give rise to malignancy. Cancer. 1993;72(12):3727–31.
Ravitch MM, Smith EI. Sacrococcygeal teratoma in infants and children. Surgery. 1951;30(4):733–62.
Galili O, Mogilner J. Type IV sacrococcygeal teratoma causing urinary retention: a rare presentation. J Pediatric Surgery. 2005;40(2):E18–20.
Flake AW, Harrison MR, Adzick NS, Laberge JM, Warsof SL. Fetal sacrococcygeal teratoma. J Pediatric Surgery.1986;21(7):563–6.
Harms D, Zahn S, Göbel U, Schneider D. Pathology, and molecular biology of teratomas in childhood and adolescence. Klinische Pädiatrie. 2006;218(06):296–302.
Yoon HM, Byeon S ju, Hwang JY, Kim JR, Jung AY, Lee JS, et al. Sacrococcygeal teratomas in newborns: a comprehensive review for the radiologists. Acta Radiologica. 2018;59(2):236–46.
Yadav DK, Acharya SK, Bagga D, Jain V, Dhua A, Goel P. Sacrococcygeal teratoma: clinical characteristics, management, and long-term outcomes in a prospective study from a Tertiary Care Center. J Indian Association of Pediatric Surgeons. 2020;25(1):15.
Tuladhar R, Patole SK, Whitehall JS. Sacrococcygeal teratoma in the perinatal period. Postgrad Med J. 2000 Dec1;76(902):754–9.
Altman RP, Randolph JG, Lilly JR. Sacrococcygeal teratoma: American Academy of Pediatrics surgical section survey—1973. J pediatric surgery. 1974;9(3):389–98.
Van Houwelingen L, Sandoval JA. Alpha-fetoprotein in malignant pediatric conditions. In: Proof and concepts in rapid diagnostic tests and technologies. IntechOpen; 2016.
Mann J, Raafat F, Robinson K, Imeson J, Gornall P, Sokal M, et al. The United Kingdom Children’s Cancer Study Group’s second germ cell tumor study: carboplatin, etoposide, and bleomycin are effective treatments for children with malignant extracranial germ cell tumors, with acceptable toxicity. J clinical oncology. 2000;18
(22):3809–18.
Gobel U, Schneider D, Calaminus G, Jurgens H, Spaar H, Sternschulte W, et al. Multimodal treatment of malignant sacrococcygeal germ cell tumors: a prospective analysis of 66 patients of the German cooperative protocols MAKEI 83/86 and 89. J clinical oncology. 2001;19(7):1943–50.
Ayed A, Tonks AM, Lander A, Kilby MD. A review of pregnancies complicated by congenital sacrococcygeal teratoma in the West Midlands region over 18 years: population‐based, cohort study. Prenatal diagnosis. 2015;35(11):1037–47.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 JOURNAL OF AFRICAN NEONATOLOGY
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
This is an open-access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.